With Bota Bio's technology platform and manufacturing capability, Yucca Elements (Bota Bio's wholly-owned subsidiary specializing in beauty and personal care ingredients) is replacing high-energy-consuming petroleum-based processes with clean biomanufacturing methods, which aligns with the sustainability trend.

Challenges
Bio-manufactured recombinant proteins are catching consumers' attention due to their hypoallergenic and high performance. However, technical challenges like low product yields, high production costs, and difficulties of functional overexpression have prevented recombinant protein products from becoming the primary functional ingredient in beauty and personal care products.
Solutions
Bota Bio quickly identified the target recombinant human protein products with the Shot Gun prediction and screening platform, expressed the target products utilizing self-developed chassis strains, and developed the fermentation and purification process. This supports Yucca's rapid launch of various bio-based protein products.
Results and impact
Yucca Elements introduced Prorylia™ FN as the first recombinant human fibronectin product on the market. It soothes sensitive skin and reinforces the skin's protective barrier. Due to its novel concept, high purity, high performance and safety, it will quickly dominate the market.
