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Strain Research Assistant
招聘人数:3
Pilot Plant Fermentation Senior Associate Engineer
招聘人数:2
Pilot Plant Downstream Purification Senior Associate Engineer
招聘人数:1
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Responsibilities:
- Responsible for developing high-throughput gene editing tools and screening methods;
- Complete the assigned tasks with high quality and perform the experiment following the SOP accurately;
- Record the experiment and data reliably;
- Corporate with the project manager to conduct data analysis and troubleshooting;
- Maintain a clean working environment;
- Complete other tasks assigned by superiors if needed.
Qualifications:
- College’s degree or above, with relevant professional background in enzyme engineering, molecular biology, microbiology, organic chemistry, biochemistry, etc.
- Work hard and have strong learning ability;
- Ability to read and use English operating software under superior's guidance;
- Self-motivated and would like to take on challenges.
Responsibilities:
- Set up and plan fermentation experiments, such as media preparation and disinfection, bioreactor preparation, and seed-strain growth and propagation;
- Monitor the progress of the fermentation process: understand different fermentation phases, changes in dissolved oxygen and take corrective actions accordingly;
- Develop and optimize high-throughput or scale-down fermentation process;
- Work closely with the strain department and analytical department to ensure successful stain optimization and process scale-up;
- Analyze, interpret, and report bench-scale fermentation process data using data analysis tools.
Qualifications:
- Master's degree in Bioengineering, fermentation engineering, chemical engineering, or microbiology with at least 3 years of working experience in a related field; OR bachelor's degree with 6+ years in related background;
- Expertise in the process parameter control and optimization in the fermentation process, experience in yeast metabolic engineering and enzyme engineering are preferred;
- Solid understanding of bioreactor system and fermentation process;
- Fluent oral English can be used as a working language.
Responsibilities:
- Execute experiments to support the development of separation processes, including filtration, extraction, distillation, chromatography crystallization, chromatography, and reactive separations, at bench scale;
- Document observable data and procedures, including the batch record, and operating procedures and fill in as SOP required;
- Responsible for equipment acceptance in the fermentation and purification department workshop, IQ, OQ, PQ, and other work, as well as daily maintenance and equipment reconfirmation;
- Perform and formulate technology transfer plans and related work from pilot production scale to large-scale manufacture;
- Participate in deviation investigation and write deviation investigation report;
- Organize and assist the computing department in establishing an advanced LIMS system to achieve the standardization of data collection, storage, retrieval, and analysis;
- Complete other tasks assigned by superiors.
Qualifications:
- Master's degree in Bioengineering, fermentation engineering, chemical engineering, or microbiology with at least 3 years of working experience in a related field; OR bachelor's degree with 6+ years in related background;
- Experienced with at least two successful fermentation projects;
- Solid knowledge of bioreactor systems and fermentation processes.
Pilot Plant Downstream Purification Associate Engineer
招聘人数:1
Pilot Plant Downstream Purification Research Assistant
招聘人数:1
Downstream Purification Research Assistant
招聘人数:3
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Responsibilities:
- Assist in establishing and operating advanced pilot downstream purification laboratories for process development and small-scale sample production;
- Assist in setting up standardized DSP operations in the pilot plant to validate process development on the bench;
- Assist in cooperating with the computation department to set up a LIMS system for data collection, storage, retrieval, and analysis;
- Assist in training DSP research assistants to support projects in the pipeline;
- Work with the bench-scale process development team to implement the process in the pilot plant, and provide hands-on training if required;
- Cooperate with the pilot plant fermentation team to develop best practices in the pilot plant;
- Assist in analyzing the DSP experiment data with DSP engineers and provide feedback to help optimize the DSP process.
Qualifications:
- Bachelor's degree in biochemistry, chemistry, pharmacy, purification, and other related majors, experience in industrial fermentation product extraction and purification is preferred;
- Proficient in at least one downstream purification unit operation (centrifugation, filtration, membrane filtration, crystallization, extraction, chromatography, distillation, etc.) and familiar with the use of at least one industrial equipment;
- Understanding the concept of lean management, lean management training, or practical experience is preferred;
- Ability to work independently, be able to promote the project process through active communication and collaboration under limited conditions and external resources;
- Excellent oral and written communication skills.
Responsibilities:
- Complete the production activities as required, ensure that the material, equipment, personnel environment, etc. meet the production needs;
- Execute the downstream production process, including the implementation of sample processing, chromatography, ultrafiltration and liquid exchange, sterilization, and filtration processes;
- Prepare the buffer solution in each process, cleaning, disinfection, and sterilization of special equipment; fill in the batch records, equipment usage records, and clearance records in time as required, all the records and usage comply with the company's standards;
- Perform the production equipment daily maintenance and repair, keep tracking and coordinating, and cooperate with related departments to carry out the maintenance, upkeep, measurement, and validation;
- Participate in process optimization and continuous improvement, and help to solve the technical problems of the production process;
- Execute the 6S management and environmental cleanliness and ensure the production site is clean and orderly.
Qualifications:
1. College's degree in biochemical, chemical, pharmaceutical, purification, and other related majors, OR technical secondary school degree with 2+ years in related background;
2. Experience in downstream purification and clean workshop is preferred;
3. Work carefully, have a strong sense of responsibility and team spirit, and be willing to actively learn new things.
Responsibilities:
- Execute the downstream production process, scale up and down, and technical transfer;
- Analytic data and cooperate with analytics teams to optimize the solution in the developing process;
- Cooperate with the pilot plant team to enlarge the experimental process, record the experimental data, and write the report.
Qualifications:
- Bachelor's degree in chemical engineering, chemical process, applied chemistry, and other related majors;
- Familiar with filtration, distillation, column separation, crystallization process development equipment, and industrial production knowledge;
- Work carefully, have a strong sense of responsibility and team spirit, and be willing to actively learn new things.
Analytics Research Assistant
招聘人数:4
Lab Research Assistant
招聘人数:1
Business development assistant
招聘人数:1
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Responsibilities:
- Perform high-throughput screening of enzyme and strain engineering projects by using laboratory automation equipment;
- Perform sample preparation and analysis procedures, communicate the data results with project managers timely;
- Support laboratory operations by preparing media, cell culture, and equipment maintenance, and troubleshooting;
- Complete the analysis experiment, experiment record, check data, report writing, and file filing accurately and efficiently.
Qualifications:
- Bachelor's degree in chemical engineering, chemical process, applied chemistry, and other related majors;
- Familiar with analytics equipment like GCMS, LCMS, UV, IR, etc.;
- Work carefully, have a strong sense of responsibility and team spirit, and be willing to actively learn new things.
Responsibilities:
- Participated in the experimental work of enzyme powder preparation, enzyme reaction, protein purification, and small molecule purification;
- Work under a superior to perform the experiment procedure safely and correctly and record as required;
- Participate in laboratory ESH construction;
- Collaborate with team colleagues or Xcross functions colleagues to execute experiments and make detailed standardized records, actively feedback on experimental results;
- Participate in the construction of the department process platform.
Qualifications:
- Bachelor's degree in biochemistry, chemistry, pharmacy, and other related majors, experience in lab management is preferred;
- Work carefully, have a strong sense of responsibility and team spirit, and excellent hands-on skills;
- Understand the basic experimental methods of biology, familiar with the use of basic laboratory equipment;
- Understand the basic experimental methods of biology, familiar with the use of basic laboratory equipment;
- Have a good team spirit and service awareness.
Responsibilities:
- Assist director in carrying out global market value analysis of potential target products, including but not limited to product market size, price, trend, domestic and foreign production providers and competitive situation, current mainstream technology routes, and emerging technology ideas;
- Product iteration risk analysis, current product pain points, and opportunity analysis (from the aspects of technology, cost, process, environmental protection, etc.)
- Focus on the company's internal business progress and needs, personnel status, work process, project-related financial and legal information, etc., and maintain effective communication with relevant departments;
- Exert subjective initiative when the project encountered resistance, communicate and coordinate with relevant department personnel, try to find solutions, and promote the implementation;
- Able to handle emergencies in a timely manner, report to superiors in a timely manner, and complete other tasks delivered by superiors.
Qualifications:
- Bachelor's degree in biomedicine, chemical, food nutrition, agriculture, and related fields;
- Have the ability to consult English literature and information, select professional and reliable information sources, and produce English analysis reports;
- Need strong comprehensive analysis ability, expert interview and expert relationship maintenance ability, excellent communication and collaboration ability, good at exerting influence in the organization;
- Have the courage and ability to solve problems, be tough and pressure resistant, be willing to achieve others, have a sense of responsibility, and have enthusiasm for high-tech innovation and entrepreneurship.
Strain Scientist
招聘人数:3
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Responsibilities:
- Closely follow the cutting-edge development and trends of enzyme engineering. Propose ideas to integrate and upgrade BOTA’s enzyme engineering technology according to the company's development strategy;
- Provide enzyme engineering and related professional technical support for different projects;
- Instruct and train the staff of the enzyme engineering team, plan experimental programs, or direct evolutionary research for different enzymes;
- Establish enzyme engineering team, R&D pipeline, and related training program, Lead the team for experiment execution;
- Cooperate with other R&D teams, and develop experimental plans based on data.
Qualifications:
- Ph.D. degree or above in enzyme engineering or related fields, Master's degrees can also be accepted if the conditions are excellent, relevant experience in industry or academia is preferred;
- Proficient in protein rational design and directed evolution, familiar with related experimental operations;
- Published research papers as the first author (including the joint first) or corresponding author, in the fields of synthetic biology, metabolic engineering, enzyme engineering, chemical biology, etc. in high-impact academic journals;
- Good English listening, speaking, reading, and writing skills;
- Have good communication and management skills, have cross-disciplinary management experience, and are good at integrating and using various resources;
- Strong motivation, passion for scientific research curiosity, and willingness to share knowledge.